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Microplate lids are used to cover plates to protect well contents from leakage, contamination, and evaporation during assay processing, incubation, or storage. Lids are available for a variety of plates, and in a variety of materials, many with specific applications, including storage, fluorescence assays, luminescence assays, microscopy, and cell culture.
A riboside form of nicotinamide a precursor of NAD and a source of vitamin B3 increases intracellular and mitochondrial NAD content in C2C12 Hepa1.6 and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1000 M decreases acetylation of FOXO1 and SOD2 but not tubulin increases NAD levels in liver and skeletal muscle and prevents body weight gain in mice fed a high-fat diet when used at a dose of 400 mg/kg per day increases NAD in the cerebral cortex and reduces cognitive deterioration in a transgenic mouse model of Alzheimers disease
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A synthetic intermediate has been used as an intermediate in the synthesis of semaglutide as well as a lipid side chain to increase the proteolysis-resistance of insulin derivatives for use in vivo
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An analytical reference standard categorized as a triazolobenzodiazepine an active metabolite of rilmazafone intended for research and forensic applications
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
A triterpenoid with diverse biological activities inhibits ACE (IC50 734 UM) cytotoxic to HepG2 HeLa and Caco-2 cancer cells (IC50s 0.14 0.18 and 0.26 mg/ml respectively) inhibits LPS-induced NO production in BV-2 microglia (IC50 13.77 UM)
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A multi-kinase inhibitor selectively inhibits MET VEGFR2 Axl and Mer (IC50s 3 15 5.8 and 0.6 nM respectively) over serine/threonine kinases for which it has no activity but does inhibit 28 additional RTKs (IC50s 3-54 nM) and additional kinases by greater than 70 at 1 UM inhibits the proliferation of SNU-5 cells (IC50 98.9 nM) and HUVECs (IC50 10.4 nM) reduces tumor volume and intratumoral MET phosphorylation in NCI H441 and SNU-5 mouse xenograft models at 3 and 10 mg/kg increases the number of peripheral B cells and CD4 T cells and decreases the number of peripheral myeloid cells in an MC-38 syngeneic mouse model of colon carcinoma at 30 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More