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Microplate lids are used to cover plates to protect well contents from leakage, contamination, and evaporation during assay processing, incubation, or storage. Lids are available for a variety of plates, and in a variety of materials, many with specific applications, including storage, fluorescence assays, luminescence assays, microscopy, and cell culture.
A disulfide bond-containing ionizable cationic lipid has been used in the generation of LNPs for plasmid delivery in vitro and in vivo LNPs containing PPPDA-O16B and encapsulating plasmids encoding RRSP increase RRSP levels and decrease Ras levels in and reduce the viability of HeLa cancer cells LNPs containing PPPDA-O16B and encapsulating plasmids encoding RRSP selectively localize to tumors over the heart liver spleen lungs and kidneys as well as decrease tumor volume without reducing body weight in an HCT116 colorectal cancer mouse xenograft model
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An internal standard for the quantification of psilocybin by GC- or LC-MS provided as a DEA exempt preparation intended for research and forensic applications
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An inhibitor of EGFRL858RT790M (IC50 1.1 nM) selective for EGFRL858RT790M over BTK wild-type EGFR FAK HER2 and HER4 (IC50s 213 226 255 392 and 704 nM respectively) but also inhibits wild-type EGFR containing an exon 19 deletion EGFRT790M containing an exon 19 deletion EGFRL585R EGFRG192A and EGFRL861Q (IC50s 1.3-12 nM) reduces tumor volume in a PDX mouse model of NSCLC at 25 and 50 mg/kg twice per day
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The lyophilized carp Vtg may be used as a positive control in immunoblotting. Freshly reconstituted Vtg may also be used as a standard in a quantitative ELISA. This product contains bovine serum albumin which will appear as a strong protein band in acrylamide gels.
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A flavonoid with diverse biological activities inhibits biofilm formation by S. aureus B. subtilis P. aeruginosa and E. coli at 32 Ug/ml rinduces cytotoxicity in SW460 and DLD-1 cancer cells (IC50s 29.41 and 30.93 UM respectively) but not HT-29 or HepG2 cancer cells (IC50s 40 UM for both) decreases LPS-induced NO production and secreted TNF-a and IL-1B levels in J774A.1 macrophages at 0.01 UM alone and in combination with NGF increases neurite outgrowths levels of GAP43 and decreases serum deprivation-induced death in PC12 cells at 10 UM
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An FXR agonist induces luminescence in a reporter assay using HEK293T cells expressing human FXR (EC50 18 nM) decreases the serum levels of ALT and total cholesterol as well as hepatic inflammation fat levels and fibrosis in a mouse model of NASH induced by a high-fat diet and CCl4 at 1 3 or 10 mg/kg per day
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More